I am a computational biologist with a focus on immunology, single-cell analysis, and immune aging. I am passionate about personalized medicine, marker discovery, drug discovery, and machine learning. I enjoy building scalable data-driven solutions and translating complex biology into actionable insights for experimental validation. I thrive on cross-disciplinary collaboration, developing robust computational pipelines, and applying multi-omics integration and GRN analysis to advance understanding of immune aging and disease, including drug repurposing and therapeutic design.

Jalil Nourisa

I am a computational biologist with a focus on immunology, single-cell analysis, and immune aging. I am passionate about personalized medicine, marker discovery, drug discovery, and machine learning. I enjoy building scalable data-driven solutions and translating complex biology into actionable insights for experimental validation. I thrive on cross-disciplinary collaboration, developing robust computational pipelines, and applying multi-omics integration and GRN analysis to advance understanding of immune aging and disease, including drug repurposing and therapeutic design.

Available to hire

I am a computational biologist with a focus on immunology, single-cell analysis, and immune aging. I am passionate about personalized medicine, marker discovery, drug discovery, and machine learning. I enjoy building scalable data-driven solutions and translating complex biology into actionable insights for experimental validation.

I thrive on cross-disciplinary collaboration, developing robust computational pipelines, and applying multi-omics integration and GRN analysis to advance understanding of immune aging and disease, including drug repurposing and therapeutic design.

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Experience Level

Expert
Expert
Expert
Expert
Expert
Intermediate

Language

English
Advanced
German
Intermediate

Work Experience

Postdoctoral Scientist at Helmholtz Centre for Infection Research (CIIM)
January 1, 2024 - Present
Identified key transcriptional regulators, genes, and pathways associated with healthy and pathological aging across five major immune cell types using large-scale single-cell datasets (>5 million cells from ~2,000 donors) via gene regulatory network inference and multi-modal analysis. Applied machine learning models to screen hundreds of compounds and identified 25 small molecules with potential rejuvenating effects, with the most potent candidate validated in wet lab.
Research Scientist at Helmholtz Zentrum Hereon
January 1, 2019 - December 31, 2024
Led a team of four ML engineers to develop a live framework for GRN inference benchmarking. Curated perturbation datasets totaling over 30 million single-cell expressions, designed metrics to evaluate GRN inference, and integrated over 10 GRN inference pipelines into a reproducible framework using Docker, Viash, and Nextflow. Built a Python workflow for time-series proteomics to identify key target proteins responsive to magnesium treatment via differential expression and GRN analysis. Awarded 1st place Judge Award ($10,000) in the 2023 Open Problems: Single Cell Perturbation Competition and authored a comprehensive design report for a VAE.
Research Engineer at Technische Universität Wien
January 1, 2018 - December 31, 2019
Managed data storage, analysis, and image processing of bone CT images.
Research Engineer at Trinity College Dublin
January 1, 2017 - December 31, 2018
Studied endothelial cell migration and proliferation in response to mechanical micro-environment using computational approaches.
Research Engineer at McGill University
January 1, 2016 - December 31, 2017
Studied vocal fold inflammation and healing using computational approaches.

Education

PhD at Kiel University
January 1, 2019 - December 31, 2022
Bachelors & Masters at Tehran Polytechnic
January 1, 2008 - December 31, 2015

Qualifications

Ireland Postgraduate Scholarship
January 1, 2017 - December 31, 2017
McGill Excellence Fellowship
January 1, 2016 - December 31, 2016
McGill Faculty of Medicine Award
January 1, 2016 - December 31, 2016
McGill Start-up Fund
January 1, 2016 - December 31, 2016
Best M.Sc. thesis award, Tehran Polytechnic
January 1, 2015 - December 31, 2015

Industry Experience

Life Sciences, Healthcare, Software & Internet, Professional Services

Experience Level

Expert
Expert
Expert
Expert
Expert
Intermediate

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