Alejandra Martin Sevilla Bilbao

Scientist at Retro Biosciences

Taught flow cytometry and cell culture techniques to differentiate iPSCs into HSCs/LT-HSCs; designed protocols to improve engraftment and lineage production; collaborated with automation, microfluidics, in vivo, screening and computational teams; presented data to internal and external advisors.

R&D Senior RA at Retro Biosciences

First hire on the hematopoietic stem cell team studying HSC aging; applied reprogramming, differentiation, small molecule treatments, mtDNA delivery with EVs; isolated and cultured human HSCs; conducted scRNA/DNA methylation and RT-qPCR analyses.

R&D Associate at Sangamo Therapeutics Cell Therapy/Immunology

Worked on allogeneic CAR-Tregs and NK inhibitory strategies for Kidney Transplantation; engineered T regulatory cells’ MHC I with ZFN knockouts and CAR-Lentiviral constructs; isolated and characterized immune cells; designed independent experiments and presented data.

Manufacturing RA at Vector Core

Engineered inactivated AAVs for production and delivery of targeted human gene therapies; conducted qPCRs for potency and tested HBS reagent; performed NGS of AAV genomes.

Researcher at UC Davis Bioinnovation Group

Created transformation and culturing handbooks for testing the production of the first insulin hormone in the microalgae Chlamydomonas reinhardtii to reduce insulin cost.

Intern at UC Davis – Dr. Maria Mudryj’s Lab

Researched regulation of AR-dependent gene expression and cellular proliferation in prostate cancer.

Technician at UC Berkeley – Dale Leitman’s Lab

Researched effects of CC6 and CC7 drugs; tested MAPK phosphorylation by Estradiol and CC6/CC7 to study receptor pathways.

R&D Intern at Aduro Biotechnology – Immunology Department

Part of STING pre-clinical project; genotyped STING knockout mice; performed lysis, PCR, purification and sequencing for BALB/c mice.