Generated lentiviral vectors for stable gene expression and performed functional assays in mammalian cells. Prepared DNA/RNA samples for NGS. Used site-directed and random mutagenesis to construct protein variant libraries and generate cold-adapted Cas12l mutants.

Postgraduate Associate at Yale University

January 1, 2024 - January 1, 2025

Investigated epigenetic regulation by analysing DNA methylation patterns in lupus and chronic kidney disease patient samples using EM-seq and methylKit. Contributed to establishment/validation of CRISPR/Cas9 knockout uveal melanoma cell lines. Studied epigenetic and expression changes at c-MET and HLA loci; analyzed bulk RNA-seq; contributed to CAR-T cell generation targeting c-MET expressing cells.

Junior Scientist at Thermo Fisher Scientific Baltics, R&D

January 1, 2021 - January 1, 2024

Participated in development of new product QC test methods, including stability studies, ensuring alignment with GMP requirements. Pre-validation/validation of QC methods; prepared GMP-compliant technical cards and analytical method validation documentation; transferred validated methods to QC teams and trained operators; supported product applications and presented results to team/management.

Junior Biotechnologist at Thermo Fisher Scientific Baltics

January 1, 2021 - January 1, 2021

Routinely performed quality control tests for products to ensure they meet specifications. Collaborated with R&D to identify root causes of test failures and implement corrective actions. Trained/mentored new team members on QC procedures. Supported enzyme bulk product manufacturing group as needed.