I am a Principal AI Engineer with over 10 years of experience spanning the full software lifecycle, from architecting scalable full-stack systems at Microsoft and GojiLabs to leading Generative AI initiatives at Triomics. I design secure, production-grade cloud architectures on AWS Bedrock and Azure, and I orchestrate complex, multi-agent LLM workflows that solve oncology and B2B challenges. I’m a cross-functional leader who bridges cutting-edge AI research with business-driven solutions, consistently delivering measurable results like 95% model accuracy and 30% efficiency gains. In my roles, I’ve built OncoLLM and data pipelines (OncoIndexer), achieved rapid go-lives, and enabled centers to screen thousands of patients monthly. I thrive in cross-functional teams, mentoring engineers and guiding AI governance and scalable deployment. I’m passionate about turning ambitious AI ideas into practical, impactful solutions.

Nicholas Florio

I am a Principal AI Engineer with over 10 years of experience spanning the full software lifecycle, from architecting scalable full-stack systems at Microsoft and GojiLabs to leading Generative AI initiatives at Triomics. I design secure, production-grade cloud architectures on AWS Bedrock and Azure, and I orchestrate complex, multi-agent LLM workflows that solve oncology and B2B challenges. I’m a cross-functional leader who bridges cutting-edge AI research with business-driven solutions, consistently delivering measurable results like 95% model accuracy and 30% efficiency gains. In my roles, I’ve built OncoLLM and data pipelines (OncoIndexer), achieved rapid go-lives, and enabled centers to screen thousands of patients monthly. I thrive in cross-functional teams, mentoring engineers and guiding AI governance and scalable deployment. I’m passionate about turning ambitious AI ideas into practical, impactful solutions.

Available to hire

I am a Principal AI Engineer with over 10 years of experience spanning the full software lifecycle, from architecting scalable full-stack systems at Microsoft and GojiLabs to leading Generative AI initiatives at Triomics. I design secure, production-grade cloud architectures on AWS Bedrock and Azure, and I orchestrate complex, multi-agent LLM workflows that solve oncology and B2B challenges. I’m a cross-functional leader who bridges cutting-edge AI research with business-driven solutions, consistently delivering measurable results like 95% model accuracy and 30% efficiency gains.

In my roles, I’ve built OncoLLM and data pipelines (OncoIndexer), achieved rapid go-lives, and enabled centers to screen thousands of patients monthly. I thrive in cross-functional teams, mentoring engineers and guiding AI governance and scalable deployment. I’m passionate about turning ambitious AI ideas into practical, impactful solutions.

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Experience Level

Expert
Expert
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Expert
Expert
Expert
Expert
Expert
Expert
Expert
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Expert
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Language

English
Fluent

Work Experience

Principal AI Engineer at Triomics
November 1, 2022 - Present
Led OncoLLM: engineered a constellation of 8 models (3B–72B) using agentic workflows for patient-level oncology reasoning; developed OncoIndexer ingestion engine for HL7, FHIR, CCDA and OCR; Achieved 95%+ accuracy in identifying correct clinical trials within the top 3; Enabled a leading cancer center to screen 7,000 patients monthly (100% coverage) and increased trial accruals by 30% YoY; Streamlined deployment to a Go-Live speed of 6 weeks and rapid deployment of 100+ oncology trials in under 7 days.
GenAI Solutions Architect at AWS - Amazon Web Services (Bedrock)
October 1, 2023 - December 1, 2025
Helped customers design generative AI solutions using Amazon Bedrock; collaborated with SA teams worldwide to accelerate delivery; gathered customer feedback to inform Bedrock improvements, and enabled secure, scalable GenAI capabilities.
GenAI Engineer at Vector.co
April 1, 2024 - December 1, 2024
Architected a multi-agent system to automate high-intent B2B outreach by synthesizing 400M+ real-time signals into personalized, context-aware LinkedIn and email sequences. Developed RAG-based pipelines to ingest unstructured CRM data and web intent signals, mapping complex relationship graphs for enterprise sales teams. Engineered a dynamic content generation engine to produce hyper-targeted ad copy at the contact level. Built LLM-powered data enrichment workflows to de-anonymize website traffic and identify named contacts and specific research topics in under 60 seconds. Optimized LLM inference and vector database retrieval using Pinecone and Weaviate to maintain sub-second latency for real-time GTM activation layers during high traffic spikes.
Prompt Engineer at InfoVision Inc
October 1, 2023 - March 1, 2024
Designed and optimized complex prompt templates using techniques like Chain-of-Thought (CoT) and Few-Shot prompting to improve model reasoning and factual accuracy. Developed automated evaluation frameworks to benchmark LLM outputs against ground-truth datasets, reducing hallucinations in production-facing applications. Collaborated with data scientists to curate instruction-tuning datasets, improving model adherence to specific brand voices and technical constraints.
Senior Software Engineer at Microsoft
February 1, 2022 - December 1, 2023
Developed and optimized backend microservices for cloud-scale infrastructure, focusing on high-availability and low-latency API performance within the Azure ecosystem. Collaborated with cross-functional teams to integrate AI-assisted features into core software products, improving developer productivity and user experience. Mentored junior engineers on distributed systems, code quality, and automated CI/CD pipelines.
Python Full Stack Developer at GojiLabs
October 1, 2012 - December 1, 2021
Led the full-stack development of 15+ custom web and mobile applications for clients ranging from startups to Fortune 500 companies. Architected scalable backend systems using Python (Django/Flask) and managed complex frontend deployments with React and Vue.js. Integrated various third-party APIs and payment gateways, ensuring robust data security and seamless user journeys across diverse product types.

Education

B.S. at Cornell University
January 1, 2008 - January 1, 2012

Qualifications

Add your qualifications or awards here.

Industry Experience

Healthcare, Software & Internet, Life Sciences, Professional Services